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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '499619fc8b0bb6699db75fca49d9e977addce8271a4f2a52e8fc6c9bb66d15df' 
  AND token = 'HIGCQTLF8tMOQDjBc2W65wCaYSFwZL+VnKyVelt/b20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}