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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea9c66329f45f736e537640f54e006b4cbe51ae61b4fec869d7ceae11c04d78' 
  AND token = 'K7lfUnYh+Xt1VnQFioSX1zre8krqIjO58cmMxO6dgUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}