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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f4126c140f8de6ad298d4d50c0d2d7a57dd74e6d1cecbd572f84b907d72775b' 
  AND token = 'zgw0hEUrlVB+6ep+7N7+Sj8GnJlgBfWbDl3gtJZEGi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}