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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4a3f8fe9d0e343a47c7dc6610b6523ec6c69ea18e06ef406c267bd4ff13602' 
  AND token = 'DEQ3GAMGa7uTi8PixxDPP9c8UZd7Y3mOezAgZ8OsFgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}