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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d14d8c62645025072f05d750972157428b56b958569afb54a0835f5ea21de65' 
  AND token = 'Jk+wiCzmf6t87ro5RZJkiRLGieqO+UGLiMYzbDpDl6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}