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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4154a277ed8fc0550f84955aa6ed044899f6e3515bca365ba108f835b7b61b6' 
  AND token = '4ReQI3iw++32kawRm7FS9g4xz1+Qmo8kwGjCX3xiohs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}