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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a0a4cfed7c25b7c3687b37328f09123e3f62805890887f6d9830271e0b29a3b' 
  AND token = 'vPOGYeRD8fvOzN1d3QjqmpvqZp0uOITbTAvn3SztVak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}