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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b67b47a19461d173d981ad9b8d32b13b15a601c460e0a53e22a90948abeacda4' 
  AND token = '2GwBYm8hyLJH+kBbR6HN3WxB9/u4KaDkymMuf1OXZuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}