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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd080817fc3c0e5c037bb1f96622f7af50a266a981c6d20b4cf1b8084240aadd6' 
  AND token = 'EHyL0105GUnMahKuy+bfhE+JAHR+lX8pntal88ISPeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}