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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10bf16e60e9ad24247ac5b7f2f74f95e3bf6d3b7bc37f68dddb0c57b4de10a06' 
  AND token = 'dSntu6lJVwnDrxSXQJ3qPQng1ik7i9wW1DspKxcxXZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}