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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6f195bc45e56897138b58e456a05c9c94629ef1aa7338f51cd399067d35339a' 
  AND token = 'RvB40zeiIU47YDma5AZRpZ5nRBxHfc3R008xYi094Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}