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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3307dfb21f66bc14d14d6249b18e93dd1afd014a07c4918af62709c531414ce2' 
  AND token = 'H1/Kpx7VI3kDKiOOHIFpmRvi3d07wnf4T7ItQHP5+Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}