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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc149eeb05587b1bd33b5f4a86eb4e86397aefafee331858488db378fb0fffd8' 
  AND token = 'dpVbJqbuvkQk6ShJlq3oRUrURad2yAxOuPxvAd/oMek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}