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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539a2c141f7a54aaf3a4465e55287d74aa9181b92d4456cad14714a78e046185' 
  AND token = 'RDcjMFCeBIlAGF/MalgErOCFrcib/Nu1mWFb/nlVzBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}