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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b82c8821f16b1a4195f9b7ecac96223692e6989dbb2407eccbe6743ce23c9d' 
  AND token = 't31waE+jyWI/6J8aOo2yaJBJk6xnU38OSscE78jOing=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}