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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc64e81d412da3ad454b2bbf2c495740662d62ad1faad9973dc757c6fc5f8d5' 
  AND token = 'kkdIgAXpsfQpCa8b0tXGotWTt0Le0OwiVQtizpBw9l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}