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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c7cfa27c5ceb1d52edc87dc2d147d253d89dcacc8ac6b549c54cca67c967201' 
  AND token = '9wWcGs55tAE4oeADx8xulF2PLC/GLtKSkCfHMlnrtIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}