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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8c610ab15016d17cb836b48bbfa884fc40f0a0f86d5b4d2ed1447f621f8334' 
  AND token = 'mGPDAX7lsCwKoMi3aRjr2z/SLSOXC47eX9lp1+OCoQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}