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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bfd856eb7be366b95913c1b5a6d146260ffc8d9777a382742026b860b385f0c3' 
  AND token = '6BCUAOle8iC6yfnS/jducnBYrPvQPgoWVqv4fc186Sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}