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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef7a55eba8cc1feb7359973e3abe865b53d92985d0a76fdd1b89dc7a444eb3fe' 
  AND token = 'DrtuEkx0HxQkLb8E+qqBFcFcxYEbYx1UI5G8TlUuUxM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}