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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d18fdb872b41cb81ee7c4de7e151cd7aa8b05cf45daa36fdb79c79b2779e867' 
  AND token = 'NJCXE95x8Z9BN6tMvVt/xZWRN2L+kUYS7ZMI+IgJfHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}