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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429866cc6d6cd65b32e223653201012d6774055f9c4200bed44c9998a649f2ad' 
  AND token = 'WBD3Zucrn2yBCrDsNNrhsa2RFBTBhA+K7Ko8ymJ2tqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}