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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d7538f59d4046ff01f7493671af857f4198955045b2fae8d3f21ecea2b87adb' 
  AND token = 'eEEUUyd7QZxx1epXUUgNF+wMecm4tZBBwgVlNSiojpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}