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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '321855bd612d0216a598109864d6120b9da92516f5b46b8e28be487d3fee4eb9' 
  AND token = 'xEfxEq3evXsDUQtj08qadnVgowLDieZMyB8e0B48PBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}