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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a185fb81c43f62f81ad6af433b7b29da6eba517d0b02ca547e1d4cad4c9263' 
  AND token = 'qBj1Ar7zUNYjwojNkzyhAd73Bqniyl8Ls4cZMQ041zM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}