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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb22ec8887fed8a4486fc74330582b54f65dc6fd4a93a0b7b24560ad5a0a0882' 
  AND token = '72k+qhXTpqsuDKHRD/Tx9zzr+ZYA8n2aWLyQw8nIZt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}