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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4224126d8ebd144216b01490e2cc5b1f520332905e8696c863f632bb07b4919' 
  AND token = 'WLK70/QHk24RkizIEd39VL3cEketJgRoV8dGbKR1VwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}