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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1da6ec77a07403c17c6714cd6d4b9c871108c021b41a12d177dcc3fb830a592' 
  AND token = '+LFMDTG336VR8I4Z9Y9aO+DLs6jIMdPyOLbYdo3WhYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}