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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c71ca5ffc29fea00f2e22b81dae966332a5be65a04dc2ceac57b3c02c939bc8' 
  AND token = 'uVCBXZ2Dx+LusJALZ9VQC5fx7znt1XvMxxU+fJnMwEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}