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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e6049b7441c0660a8a756fe39becfa933ee65fa0e2a58fccd7fd74971944af5' 
  AND token = '6jo2FYIrIm5tFEdkr58I7UlFx8+Hlhwf7lTbHsi9ZHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}