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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '432d447f7bb443114e1580257df48b062bac2f10bc25e63f59d035e03ab0a710' 
  AND token = 'smqmTP6OOA4seZI0pmqw4D/rO32qEoRdlFlImK4auDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}