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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2d802daee4a3a70db7caf2af17421d13950dd58d93a64b1de2df24f6c9e2fd9' 
  AND token = 'AA9+IVVAJCHcDlVb6IbjSSsiZhX2nXuC8iAr+cEBMSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}