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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a19e9488f5aef9ab04a6dfadde9cfb8800f4cff342a6e4ae5990cdd6073cc65' 
  AND token = 'elO+MrOXGEvB4rxUtzwRbDaKRHnw3FySLAoQ7W1sPRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}