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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f182e219c9d658e5899d30b7dd134bb43297b14e40ae7ca727986d8358c814' 
  AND token = 'dSCutCd1C38LC3z1Plc3gXFatBzEVz+56SCCCdcVRAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}