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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '540189d8a08e859be313801e203eb37ef6fb0d27fb11923ac12a02e7e23e0c26' 
  AND token = 'znRtnH+E6QHC7P4BDbJIKgf/GbR11an4I08GIh40PF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}