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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65dc33d47a9f996d6ee0f0e24758d2cdbeeca22d5c01c3b7f64887602fba7e2' 
  AND token = '45CpxOA+ieEI/iVXXgq6syUkDXMDYRHHinipqIj3ZjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}