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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acec21b10a1911babb47166d6c42d56e1d8c95c6902ddade63fe4d90d22d0dc3' 
  AND token = '+fwuXhwVfANSycra9myQD3/YKgquaA+mgP63By9caFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}