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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b04586a51557f9a2f85f5d3218618c282840c3b9e9d42c66395d104ae8a4ab4' 
  AND token = 'REa9DRLy+Ch/TQ40HkOlFbbYmgPIAhVV7UgncNI8rsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}