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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e485dfb5cfa9ad1a87d618231109a501c5acdd1a3a65df5e897e61ab40226e63' 
  AND token = 'u42cDLKh2YgYF2B7ETRAKv/bVf33cvehbODiLlfaxdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}