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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5bbc988eb271e659885d3fe55b47df8b54ee5ede1e1fd694a47829554a1db8a' 
  AND token = '48SVJkT43Y/Nso9IBmzcDuy/JVxfQ6Arrxqp57GL6Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}