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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a14cfd81bc21e051507ebb43236c9b74469c3aecedd4e146040a8b535f19fd39' 
  AND token = 'N8jZyBey/YoCJRE2c9YsSmecD2zqGftF5G1PxE2WqlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}