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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca7fe6d4291506b27c9bc4f05d724f99b20496e74538e985a9028c596b517c0e' 
  AND token = 'sRW6Kl4O+EtDon5zW8Bof8saCoIwtM7jsZS2UOOcG7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}