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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32c781e0521100013f5dbdc43a992b67511f83aa27eb1d17ae28d62eadbd14b8' 
  AND token = 'LSiyfWRnzZnUmBCmYqLq4NyMijXYsq0NXjOhWWb4iLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}