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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47cdc27ca3208d7bed3950760ed4ce09f5555d10046a4882c97b76af31e6aaa2' 
  AND token = '5ar4U8NUc1sUzmO+k4mMARVR6tzTXLiS8xV6ahuxA0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}