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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022e8f8c000a25a895592d8443a932568d7863f0e339aae3b9b8f246d660016d' 
  AND token = 'cd6WCZB//tfELXn76Jh3IpqEsXcfJeqYOraQRU3VvjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}