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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38cfa2f08c0ef5f55b69465df090d8042136b1533000edde782f3c1ce8ef799b' 
  AND token = 'MRn0MjUAM9L32VW4rGJ8sHZv66W7hHei0OnZ9FmBfsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}