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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4448940d6485450b71933bdf05b8d1495632f54acac62db5905df30a44dec5a3' 
  AND token = 'vnP20U9uuXj7dbB9Hqj1hOvY4uCsl459E1GyS14X3Bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}