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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7e21b503080ecd9e73e92e2a36a77452d892d8bf4da832761be73f1e86ca40' 
  AND token = 'esvcZxnaezmzzyDfjYoDOd7uz9urvGZVJOys1AcmyQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}