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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42570d763b436a6b54cf8e599a3100a26b01247618474ed88a20448381b61dfc' 
  AND token = 'rYo0yf5yAIHXAltPbFpCrBG1PX2vxTVZbYrzTtbAKQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}