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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e8151e8560fb69bde232e6053c7d8a2e0c1c1f0cccb756932a24c8114a0229e' 
  AND token = 'JpQPdgvDQAStNalu0mL6IDXe6YL9r40C8I+TAsrCdNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}